您现在的位置: 首页 > 网站导航收录 > 百科知识百科知识
(ptm是什么意思)-ptm职位什么意思
细胞,抑制,肿瘤(ptm是什么意思)-ptm职位什么意思
发布时间:2016-12-08加入收藏来源:互联网点击:
22. Pan, C., et al., Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest, 2019. 129(6): p. 2431-2445.
23. Lin, R., et al., 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol, 2015. 17(11): p. 1484-96.
24. Gao, X., et al., gamma-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell, 2019. 76(6): p. 857-871 e9.
25. Zhao, S., et al., Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature, 2020. 579(7800): p. 586-591.
26. Lin, R., et al., The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells. Mol Cell, 2018. 69(6): p. 923-937 e8.
27. Chung, C., et al., Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas. Cancer Cell, 2020. 38(3): p. 334-349 e9.
28. Elia, I., et al., Breast cancer cells rely on environmental pyruvate to shape the metastatic niche. Nature, 2019. 568(7750): p. 117-121.
29. McBrayer, S.K., et al., Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell, 2018. 175(1): p. 101-116 e25.
30. Su, R., et al., R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell, 2018. 172(1-2): p. 90-105 e23.
31. Losman, J.A., et al., (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible. Science, 2013. 339(6127): p. 1621-5.
32. Sciacovelli, M., et al., Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition. Nature, 2016. 537(7621): p. 544-547.
33. Sulkowski, P.L., et al., Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. Nat Genet, 2018. 50(8): p. 1086-1092.
34. Jiang, Y., et al., Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation. Nat Cell Biol, 2015. 17(9): p. 1158-68.
35. Bruning, U., et al., Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation. Cell Metab, 2018. 28(6): p. 866-880 e15.
36. Liao, C., et al., Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer. Cancer Discov, 2020. 10(11): p. 1706-1721.
37. Li, J., et al., DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling. Clin Cancer Res, 2020. 26(14): p. 3843-3855.
38. Peterson, T.R., et al., mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell, 2011. 146(3): p. 408-20.
39. Gentric, G., et al., PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers. Cell Metab, 2019. 29(1): p. 156-173 e10.
40. Johnson, M.O., et al., Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism. Cell, 2018. 175(7): p. 1780-1795 e19.
41. Cai, W.F., et al., Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion. Cell Res, 2018. 28(8): p. 865-867.
42. Wang, X., et al., alpha-Ketoglutarate-Activated NF-kappaB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development. Mol Cell, 2019. 76(1): p. 148-162 e7.
43. Jin, L., et al., The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Mol Cell, 2018. 69(1): p. 87-99 e7.
44. Lee, J.S., et al., Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures. Cell, 2018. 174(6): p. 1559-1570 e22.
45. Li, G., et al., p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage. Proc Natl Acad Sci U S A, 2021. 118(28): p. e2019822118.
46. Ducker, G.S. and J.D. Rabinowitz, One-Carbon Metabolism in Health and Disease. Cell Metab, 2017. 25(1): p. 27-42.
47. Zheng, Y., et al., Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells. Cell, 2018. 175(6): p. 1546-1560 e17.
48. Mentch, S.J., et al., Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism. Cell Metab, 2015. 22(5): p. 861-73.
49. Katoh, Y., et al., Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. Mol Cell, 2011. 41(5): p. 554-66.
50. Wang, Z., et al., Methionine is a metabolic dependency of tumor-initiating cells. Nat Med, 2019. 25(5): p. 825-837.
51. Lee, J.V., et al., Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metab, 2014. 20(2): p. 306-319.
52. Carrer, A., et al., Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer Discov, 2019. 9(3): p. 416-435.
53. Sivanand, S., et al., Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination. Mol Cell, 2017. 67(2): p. 252-265 e6.
54. Zhang, H., et al., Ketogenesis-generated beta-hydroxybutyrate is an epigenetic regulator of CD8( ) T-cell memory development. Nat Cell Biol, 2020. 22(1): p. 18-25.
55. Zhang, D., et al., Metabolic regulation of gene expression by histone lactylation. Nature, 2019. 574(7779): p. 575-580.
56. Wang, Y., et al., KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase. Nature, 2017. 552(7684): p. 273-277.
57. Tan, M., et al., Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metab, 2014. 19(4): p. 605-17.
58. Tan, M., et al., Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell, 2011. 146(6): p. 1016-28.
本文到此结束,希望对大家有所帮助呢。
下一篇:返回列表
相关链接 |
||
网友回复(共有 0 条回复) |